Abstract #1093100: A Study on Prevalence of Asymptomatic Pulmonary Hypertension in Patients of Metabolic Syndrome With Obstructive Sleep Apnoea

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چکیده

To find out the presence of asymptomatic pulmonary hypertension by 2D ECHO who have metabolic syndrome WHO diagnostic criteria (presence insulin resistance plus any following two criteria, namely hypertension, hypertriglyceridemia, low HDL, BMI >30 mg/kgm2, urinary albumin: creatinine ratio > 30 mg/dl) and obstructive sleep apnoea done polysomnography. The secondary objective is to assess diabetes status in patients with hypertension. Study population: All attending tertiary care outpatient department for type 2 / pre-diabetes/dyslipidemia/hypertension/obesity are screened features. Patients chronic disease, coronary artery prior history pathological lung disease excluded from study. meet assessed Echocardiography As a pilot study, 34 consecutive found Metabolic Syndrome (MS) criteria. 28 (82%) MS Obstructive Sleep Apnoea (OSA). 14 (50%) them Pulmonary Hypertension (PHT) Echocardiography. Prediabetes more prevalent, 22 (65%) among than (32%). but one patient has no OSA moderate This >10 yr duration, hence was done, remaining 05 pre-diabetic evidence (2D not as they do criteria). Asymptomatic PHT 6/12(50%) diabetics 8 /22 (Manuscript File Click here view linked References 36%) prediabetes. Except one, duration all less 10 prediabetes recently detected within year. Our findings suggest that associated 4-fold higher occurrence OSA. It prevalent pre-diabetes this cohort. detection association DM, requires further longitudinal studies pathophysiology heart failure preserved ejection fraction these subsets patients. prevalence cases increases increasing severity OSA, therefore, early will be beneficial.

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ژورنال

عنوان ژورنال: Endocrine Practice

سال: 2021

ISSN: ['1530-891X', '1934-2403']

DOI: https://doi.org/10.1016/j.eprac.2021.08.016